Despite advancements in medical treatments, the role of lifestyle factors, particularly dietary adjustments, remains relatively unexplored in the treatment of Psoriasis. Many individuals have turned to dietary modifications, with the Mediterranean diet (MeD) gaining attention for its anti-inflammatory properties. Studies suggest that adhering to the MeD may alleviate psoriasis severity, potentially through its modulation of the gut microbiome.

Research indicates notable changes in the gut microbiome of patients with psoriasis, characterized by decreased microbial diversity and alterations in bacterial composition. Patients with psoriasis typically exhibit imbalances, including a higher Firmicutes/Bacteroidetes ratio and reduced levels of beneficial bacteria like Akkermansia muciniphila. Conversely, studies exploring the impact of the MeD on the gut microbiome have shown increased diversity and richness, along with favorable shifts towards anti-inflammatory species. These changes induced by the MeD could contribute to its anti-inflammatory effects, possibly alleviating psoriasis symptoms. While further investigation is warranted, recommending the MeD to interested psoriasis patients seems sensible given its broader health benefits and potential to mitigate disease severity.

Reference: Kranyak A, Haran K, Smith P, Johnson C, Liao W, Bhutani T. The Mediterranean Diet as a Potential Solution to the Gut Microbiome Dysbiosis in Psoriasis Patients. Journal of Psoriasis and Psoriatic Arthritis. 2024;0(0). doi:10.1177/24755303241226626