Patients with psoriasis are at a significantly higher risk of migraine, particularly migraine with aura, according to a recent case-control study conducted in Iran. The study found that 21.2% of patients with psoriasis experienced migraine, compared to 8.7% of age- and gender-matched controls without psoriasis. Logistic regression analysis revealed that psoriasis patients had a 2.79 times higher odds of experiencing migraine than those without psoriasis. The association between migraine and psoriasis severity was also observed, with higher disease severity correlating with increased migraine risk, especially in patients with psoriatic arthritis (PsA), who had the highest odds of migraine.

The researchers emphasized the potential role of chronic systemic inflammation as a shared pathogenic mechanism between psoriasis and migraine, particularly in patients with PsA. These findings highlight the importance of further research to better understand the relationship between psoriasis and migraine and its potential implications for clinical management.

Reference: Rosenberg J. Migraine More Common in Patients With Psoriasis, Say Findings. AJMC. Updated February 11, 2023. Accessed April 29, 2024. https://www.ajmc.com/view/migraine-more-common-in-patients-with-psoriasis-say-findings