Psoriasis presents complex challenges with profound physical and emotional impacts, despite progress in understanding its mechanisms and treatment development. The future of psoriasis treatment holds promise with novel biologic agents like IL-23 inhibitors and RORγt inhibitors, offering enhanced efficacy and better disease control. Advancements in topical treatments, including microneedles and nanoparticle-based carriers, show potential for improving drug delivery and effectiveness while minimizing side effects. Biomarker identification using multi-omics technologies offers personalized treatment approaches, aiding in predicting treatment response and guiding therapeutic decisions.

Collaboration among stakeholders is vital to translating these advancements into clinical practice and addressing challenges such as treatment resistance, adverse effects, and high costs, ultimately improving outcomes and quality of life for individuals with psoriasis. By embracing emerging trends and tailoring treatments to individual needs, significant strides can be made in optimizing psoriasis management.

Reference: Lee HJ, Kim M. Challenges and Future Trends in the Treatment of Psoriasis. Int J Mol Sci. 2023 Aug 28;24(17):13313. doi: 10.3390/ijms241713313. PMID: 37686119; PMCID: PMC10487560.