Challenges in Assessing Psoriasis Impact: A Review of Patient-Reported Outcome Measures

This article systematically reviews patient-reported outcome (PRO) measures developed and validated for assessing the impact of psoriasis on physical, social, and psychological functioning. Through a comprehensive search of databases like PubMed, PsycINFO, and CINAHL, 45 PRO measures were identified, with 16 specific to psoriasis. Notably, no single PRO measure was found to adequately capture the full impact of psoriasis on patient well-being, highlighting the need for a valid, sensitive, and specific PRO measure to guide comprehensive clinical management. The review emphasizes the importance of PRO measures in guiding treatment decisions by assessing various aspects of patients’ well-being. Despite the identification of numerous PRO measures, the lack of evidence for their validity, reliability, and sensitivity to change poses challenges in their clinical utility. Moving forward, there is a pressing need for the development of a PRO measure that encompasses the multidimensional impact of psoriasis on patient well-being to facilitate more comprehensive clinical management strategies.

Reference: Kitchen H, Cordingley L, Young H, Griffiths CE, Bundy C. Patient-reported outcome measures in psoriasis: the good, the bad and the missing! Br J Dermatol. 2015;172(5):1210-21. doi: 10.1111/bjd.13691. Epub 2015 Apr 12. PMID: 25677764.